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Symbol Name ID |
Abcb1a
ATP-binding cassette, sub-family B member 1A MGI:97570 |
| Darker colors indicate more annotations |
| Human Phenotypes | Neutrophilia |
Leukocytosis |
Abnormal granulocyte morphology |
Abnormal basophil morphology |
Acute lymphoblastic leukemia |
Ph-positive acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Chronic myelogenous leukemia |
Myeloproliferative disorder |
Pericarditis |
Lymphadenopathy |
Splenomegaly |
Inflammation of the large intestine |
Crohn's disease |
Peritonitis |
Subacute progressive viral hepatitis |
Pancreatitis |
Iridocyclitis |
Epididymitis |
Erysipelas |
Erythema nodosum |
Skin rash |
Meningitis |
| Disease(s) Associated with ABCB1 | |||||||||||||||||||||||
| acute lymphoblastic leukemia | |||||||||||||||||||||||
| Behcet's disease | |||||||||||||||||||||||
| chronic myeloid leukemia | |||||||||||||||||||||||
| familial mediterranean fever | |||||||||||||||||||||||
| hepatocellular carcinoma | |||||||||||||||||||||||
| inflammatory bowel disease 13 |
| Mouse Phenotypes | large intestinal inflammation |
colitis |
increased eosinophil cell number |
decreased gamma-delta intraepithelial T cell number |
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology |
abnormal lymphocyte physiology |
increased IgA level |
increased IgE level |
increased IgG1 level |
increased IgG2a level |
increased IgG2b level |
increased IgG2 level |
increased IgG3 level |
increased IgM level |
increased immunoglobulin level |
|
| Availability | Mouse Genotype | |||||||||||||||
| Abcb1amds/Abcb1amds | ||||||||||||||||
| Abcb1atm1Bor/Abcb1atm1Bor | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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